Brian Trainor

Associate Professor
Department of Psychology
University of California
One Shileds Ave.
Young Hall
Davis, CA.

Office phone: 530-752-1672
Email: Brian

Brian Trainor, Behavioral Neuroendocrinology Lab

University of California, Davis, CA.

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UC Davis

 

Current Research Interests

Sex Differences in Effects of Social Stress

One important feature of many mood disorders is that women are almost twice as likely as men to be affected. For a variety of reasons however, most animal models examining neurobiological mechanisms related to depression focus on males. Indeed, there is an urgent need for the development of model systems in which behaviors related to depression and anxiety can be studied in both sexes. We are studying how social stress affects behavior in male and female California mice (Peromyscus californicus). Current research projects are investigating how sex differences in neurobiological responses to stress mediate long term behavioral changes, such as social withdrawal. Diferent projects are focusing the roles of the dopaminergic, neuropeptide, neurotrophin, and endogenous opioid systems. We are using the unique biology of the California mouse to examine sex differences in neurobiological mechanisms that mediate the effects of social stress on affective behaviors.

Methods used

Multilabel immunohistochemistry

Intracerebral infusions

Neuroantomical tracing

Social interaction and discrimination testing

Barnes maze for spatial memory

Conditioned place preference/aversion

ELISA and RIA

Western blotting

qPCR and next generation sequencing

 

Media coverage of research

Links between stress and breast cancer: UCDMC Synthesis

Science Signal Transduction Knowledge Environment Editor's Choice

Science Daily


Training

Post-doc: Ohio State University, Randy Nelson
Post-doc: Harvard University, Hans Hofmann
PhD: University of Wisconsin, Cathy Marler
MS: University of Nebraska, Alex Basolo
BS: University of Texas: Mike Ryan

 

 

 

Photos by Nicholas DiRienzo and Sarah Laredo